IL-17: New Insights into Advances from diagnostics to therapeutics of inflammatory diseases

Abstract

Interleukin 17 (IL-17) is a proinflammatory cytokine having 6 related cytokines. Over the past few years, the roles of IL-17 go beyond not merely activating inflammation but also progression of disease. Evidence is mounting that IL-17 has significant roles in causing and developing various inflammatory diseases. And recently, specific inhibitions of IL-17 have improved in the treatment of these diseases. This review aims to highlight the general trends of these treatments as well as the various diseases related to IL-17 inflammatory actions, and interactions with other cytokines that perform similar functions.